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HomeCyazofamid vs Cymoxanil: How They Compare for Downy Mildew

Cyazofamid vs Cymoxanil: How They Compare for Downy Mildew

Two actives with different strengths. Cyazofamid is a protectant, cymoxanil is a curative. Here's what that means for your fungicide program.

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What Each Active Does

Cyazofamid belongs to the cyanoimidazole chemical class. It works mainly as a protectant, stopping spore germination and early infection. You'll see it used against oomycete diseases like downy mildew and late blight on vegetables, grapes, and potatoes.

Cymoxanil is a cyanoacetamide oxime. It's a local systemic with curative and antisporulant activity. It penetrates leaves quickly and can stop early infections. It's often mixed with protectants to add kickback activity.

Side by Side Comparison

AspectCyazofamidCymoxanil
Chemical classCyanoimidazoleCyanoacetamide oxime
Mode of actionInhibits complex III in fungal respirationInhibits nucleic acid synthesis
Main targetsOomycetes: downy mildew, late blightOomycetes: downy mildew, late blight
Systemic or contactContact and protectantLocal systemic, curative
Typical formulationSC, WGWP, WG, often in mixtures
Resistance management roleUse in rotation with other FRAC groupsLow risk alone, but usually mixed
Tank-mix notesCompatible with many protectantsOften paired with protectants like mancozeb or famoxadone

Choosing Between Them and CHICO Products

Pick cyazofamid when you need strong preventive control and want a different FRAC group in your rotation. Pick cymoxanil when you need curative action or a short pre-harvest interval. In practice, many growers use both.

CHICO offers a ready cyazofamid cymoxanil mixture: CYMA® Cyazofamid 10% + Cymoxanil 50% 60% WDG. It combines protectant and curative activity for cucumber, potato, grape, and other crops. For a cymoxanil-based option without cyazofamid, see CYFA® Cymoxanil 30% + Famoxadone 22.5% 52.5% WDG. Check the label of your registered product for local use rates.

Questions Buyers Ask

Can I tank-mix cyazofamid and cymoxanil?

Yes, they're often mixed. Cyazofamid gives protectant control, cymoxanil adds curative action. CHICO's CYMA® 60% WDG is a ready formulation, so you don't need to mix them yourself.

Which one is better for resistance management?

Both have a place. Cyazofamid is a FRAC group 21 fungicide, so rotate it with other groups. Cymoxanil is usually mixed with a protectant, which helps delay resistance. Using a pre-mix like CYMA® can simplify your program.

Does CHICO sell cyazofamid alone?

No, CHICO doesn't offer a single-active cyazofamid product. The CYMA® 60% WDG contains cyazofamid 10% plus cymoxanil 50%, which covers both protectant and curative needs in one granule.

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